Catedrática Auxiliar | Escuela de Salud y Ciencias

Ext. 5231
noemi.soto@sagrado.edu

La doctora Soto Nieves posee un bachillerato en Biotecnología Industrial de la Universidad de Puerto Rico, Recinto de Mayagüez, una maestría en genética molecular y un doctorado en Ciencias Biomédicas con especialidad en Genética, Biología Celular Molecular e Inmunología de Albert Einstein College of Medicine en New York. Además, ha colaborado en proyectos de investigación en Puerto Rico y Estados Unidos.

Proyectos de investigación

Detection and Quantification of Coliforms at San Juan Bay Estuary in Puerto Rico. Collaboration with Environmental Protection Agency and Environmental Research Laboratory of Natural Resources of Puerto Rico. Universidad del Sagrado Corazón. (jul 2020 al presente) Profesora asistente

Aza-podophylotoxin derivate compounds as potent apoptosis inducers in cancer cell lines.
Isolation and cultivation of Pyrodinium bahamense Proteomic analysis of tissue from autoimmune clinical patient

Universidad Ana G. Méndez. (junio 2013 a julio 2020) Profesora asistente

Transcriptional Complexes that Control the Expression of Anergy-Inducing genes. Albert Einstein College of Medicine-Yeshiva University, Bronx, New York (enero 2004 a septiempre 2007) Estudiante graduada

TGF-β Signaling Pathway Characterization in Epithelial Cells. Albert Einstein College of Medicine-Yeshiva University, Bronx, New York. (agosto 2002 a diciembre 2003) Estudiante graduada

Role of CCR8 in inflammation. Immunology and Rheumatology Department at Merck Research Laboratories, Rahway, New Jersey (febrero 2001 a agosto 2001) Investigadora

Expression of variant protein (human centrin 2 mutant T169/A, S170/A) using the fermenter vessel, and its isolation and characterization. Universidad de Puerto Rico en Mayagüez. (agosto 1999 a mayo 2000) Estudiante subgraduada

Development of Reporter Gene Technology to Characterize Genes Transcriptionally regulated by temperature. Northwestern University, Evanston, Illinois (junio 1999 a agosto 1999) Estudiante subgraduado de Investigación de Verano

Biological Control of Potato Scab Disease by Streptomyces bacteria.University of Minnesota, St Paul, Minnesota. (junio 1998 a agosto 1998). Estudiante subgraduado de Investigación de Verano

Publicaciones arbitradas

Soto-Nieves N, Bandyopadhyay S, Rao A, Macian F. Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance. J Exp Med. 2009 Apr 13;206(4):867-76.

Olabisi OA, Soto-Nieves N, Nieves E, Yang TT, Yang XY, Yu RY, Suk HY, Macian F, Chow CW. Regulation of Transcription Factor NFAT by ADP-Ribosylation. Mol Cell Biol. 2008: Feb 25.

Soto-Nieves N, Puga I, Macian F. (2007) The NFAT family of transcription factors. In: S. Offermans and W. Rosenthal Eds. Encyclopedics Reference of Molecular Pharmacology, 2nd Ed. Elsevier.

Bandyopadhyay S, Soto-Nieves N, Macian F. Transcriptional regulation of T cell tolerance. Semin Immunol. 2007 Jun;19(3):180-7.

Bandyopadhyay S, Dure M, Paroder M, Soto-Nieves N, Puga I, Macian F. Interleukin 2 gene transcription is regulated by Ikaros-induced changes in histone acetylation in anergic T cells. Blood. 2007 Apr 1;109(7):2878-86.

Zavadil J, Cermak L, Soto-Nieves N, Bottinger EP. Integration of TGF-beta/Smad and Jagged1/Notch signaling in epithelial-to-mesenchymal transition. EMBO J. 2004 Mar 10;23(5): 1155-65