Assistant Professor | School of Health and Sciences
Ext. 5231
noemi.soto@sagrado.edu
Dr. Soto Nieves holds a bachelor's degree in Industrial Biotechnology from the University of Puerto Rico, Mayagüez Campus, a master's degree in molecular genetics and a doctorate in Biomedical Sciences with a specialty in Genetics, Molecular Cell Biology and Immunology from Albert Einstein College of Medicine in New York. In addition, she has collaborated in research projects in Puerto Rico and the United States.
Research Projects
Detection and Quantification of Coliforms at San Juan Bay Estuary in Puerto Rico. Collaboration with Environmental Protection Agency and Environmental Research Laboratory of Natural Resources of Puerto Rico. Universidad del Sagrado Corazón Heart. (Jul 2020 to present) Assistant Professor
Aza-podophylotoxin derivative compounds as potent apoptosis inducers in cancer cell lines.
Isolation and cultivation of Pyrodinium bahamense Proteomic analysis of tissue from autoimmune clinical patient
Ana G. Méndez University. (June 2013 to July 2020) Assistant Professor
Transcriptional Complexes that Control the Expression of Anergy-Inducing genes. Albert Einstein College of Medicine-Yeshiva University, Bronx, New York (January 2004 to September 2007) Graduate student
TGF-β Signaling Pathway Characterization in Epithelial Cells. Albert Einstein College of Medicine-Yeshiva University, Bronx, New York. (August 2002 to December 2003) Graduate student
Role of CCR8 in inflammation. Immunology and Rheumatology Department at Merck Research Laboratories, Rahway, New Jersey (February 2001 to August 2001) Researcher
Expression of variant protein (human centrin 2 mutant T169/A, S170/A) using the fermenter vessel, and its isolation and characterization. University of Puerto Rico in Mayagüez. (August 1999 to May 2000) Undergraduate student
Development of Reporter Gene Technology to Characterize Genes Transcriptionally regulated by temperature. Northwestern University, Evanston, Illinois (June 1999 to August 1999) Summer Research Undergraduate Student
Biological Control of Potato Scab Disease by Streptomyces bacteria.University of Minnesota, St Paul, Minnesota. (June 1998 to August 1998). Summer Research Undergraduate Student
Peer-reviewed publications
Soto-Nieves N, Bandyopadhyay S, Rao A, Macian F. Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance. J Exp Med. 2009 Apr 13;206(4):867-76.
Olabisi OA, Soto-Nieves N, Nieves E, Yang TT, Yang XY, Yu RY, Suk HY, Macian F, Chow CW. Regulation of Transcription Factor NFAT by ADP-Ribosylation. Mol Cell Biol. 2008: Feb 25.
Soto-Nieves N, Puga I, Macian F. (2007) The NFAT family of transcription factors. In: S. Offermans and W. Rosenthal Eds. Encyclopedics Reference of Molecular Pharmacology, 2nd Ed. Elsevier.
Bandyopadhyay S, Soto-Nieves N, Macian F. Transcriptional regulation of T cell tolerance. Semin Immunol. 2007 Jun;19(3):180-7.
Bandyopadhyay S, Dure M, Paroder M, Soto-Nieves N, Puga I, Macian F. Interleukin 2 gene transcription is regulated by Ikaros-induced changes in histone acetylation in anergic T cells. Blood. 2007 Apr 1;109(7):2878-86.
Zavadil J, Cermak L, Soto-Nieves N, Bottinger EP. Integration of TGF-beta/Smad and Jagged1/Notch signaling in epithelial-to-mesenchymal transition. EMBO J. 2004 Mar 10;23(5): 1155-65